FATE-MAPPING AND FUNCTIONAL DISSECTION REVEAL PERILOUS INFLUENCE OF TYPE I INTERFERON SIGNALING IN MOUSE BRAIN AGING

Fate-mapping and functional dissection reveal perilous influence of type I interferon signaling in mouse brain aging

Abstract Background Aging significantly elevates the risk of developing neurodegenerative diseases.Neuroinflammation is a universal hallmark of neurodegeneration as well as normal brain aging.Which branches of age-related neuroinflammation, and how they precondition the brain toward pathological progression, remain ill-understood.The presence of el

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Contrasting impacts of reindeer grazing in two tundra grasslands

Plant communities in Arctic and alpine areas are changing due to higher temperatures and longer vegetation periods and it is uncertain how this will affect plant-herbivore dynamics.For instance, relatively fast-growing, deciduous shrub species that are the gruvi golden lager most responsive to warming may also be the most targeted by herbivores suc

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Monitoring feeding behaviour of dairy cows using accelerometers

Monitoring cow behaviour has become increasingly important in understanding the nutrition, production, management of the well being, and overall health of dairy cows.Methods of assessing behavioural activity have changed in recent years, favouring automatic recording techniques.Traditional methods to measure behaviour, such as direct observation or

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